Contraindicated. CYP3A4 is accountable for the development and elimination of cariprazine's Lively metabolites. The effect of CYP3A4 inducers on cariprazine publicity has not been evaluated along with the net result is unclear.pentobarbital will lower the extent or impact of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use

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